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Pentasa (Mesalamine)


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What is/are Pentasa?

MESALAMINE is used to treat the pain and inflammation caused by ulcerative colitis. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • kidney disease
  • pyloric stenosis
  • an unusual or allergic reaction to mesalamine, salicylates, other medicines, sulfites, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not crush or chew. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • digoxin

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • bloody diarrhea
  • chest pain
  • difficulty breathing, wheezing
  • fever
  • pain or difficulty passing urine
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • nausea, vomiting
  • stomach gas
  • stomach pain or cramps

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better after several days. There is usually an improvement in 3 to 21 days. You may need about 6 weeks of treatment to get good results.

Do not change the brand of this medicine that you are taking without talking to your doctor or health care professional. All brands do not have the same dose.

You may notice the empty shell from this medicine in your stool. If this happens frequently, you should contact your doctor or health care professional.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

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