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Reglan (Metoclopramide)


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  Generic Reglan (METOCLOPRAMIDE) is a gastrointestinal stimulant used to treat gastroesophageal reflux and erosions/ulcers of the esophagus. It is also used to treat nausea, vomiting, heartburn, prolonged fullness after meals, and loss of appetite in patients with diabetes (diabetic gastroparesis). It may also be used to treat other conditions as determined by your doctor.

Drug Uses
Reglan is used for treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn) in patients who do not respond to other treatment. It is also used to treat nausea, vomiting, heartburn, prolonged fullness after meals and for treatment of symptoms associated with a certain digestive problem in diabetic patients (diabetic gastroparesis). It may also be used for other conditions as determined by your doctor.

How Taken
Use Reglan as directed by your doctor. Take Reglan 30 minutes before a meal. It may take several days to weeks for Reglan to work. Do not stop taking Reglan without checking with your doctor.

Warnings/Precautions
Before taking Reglan, tell your doctor or pharmacist if you have any medical conditions, especially if you have allergies to medicines, foods, or other substances, if you are allergic to any ingredient in Reglan, if you have depression, asthma, heart failure, high blood pressure, diabetes, Parkinson disease, blood problems (eg, porphyria), kidney problems, or low levels of an enzyme called Reglan reductase, if you are pregnant, planning to become pregnant or are breast–feeding. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Reglan while you are pregnant. This medicine is found in breast milk. If you are or will be breast–feeding while you use Reglan, check with your doctor. Discuss any possible risks to your baby. Some medicines may interact with Reglan. Therefore tell your doctor of all prescription or nonprescription medicine, herbal preparation, or dietary supplement that you are taking. Do not take Reglan if you have seizures (eg, epilepsy), bleeding, blockage, or perforation in your stomach or intestines, or tumors on your adrenal gland (pheochromocytoma), if you are taking cabergoline, pergolide or medicines, such as phenothiazines, that may cause extrapyramidal reactions (abnormal, involuntary muscle movements of the head, neck, or limbs). Reglan may affect your blood sugar. If you are a diabetic, check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Reglan. Symptoms may include fever, stiff muscles, confusion, abnormal thinking, fast or irregular heartbeat, and sweating. Contact your doctor at once if you have any of these symptoms. Lab tests, including liver and kidney function tests may be performed while you use Reglan. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Reglan should not be used in children younger than 15 years old, safety and effectiveness in these children have not been confirmed.

Missed Dose
If you miss a dose take it as soon as you remember. However if it is almost time for the next dose, skip the Missed Dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects
Some of the Possible Side Effects are- Agitation, anxiety, breast growth, changes in menstrual flow, confusion, diarrhea, dizziness, drowsiness, foot tapping, frequent urination, headache, inability to sit still, jitteriness, lack of energy, loss of bladder control, nausea, pacing, restlessness, sleeplessness, spontaneous flow of breast milk, tiredness. Contact your doctor if any of these or other side effects occur. If you experience any of the following serious side effects, you should seek medical attention immediately- allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue), altered mental abilities, including lack of response to surroundings, breathing problems, depression with thoughts of suicide, fever, fluid retention, hallucinations, hives, impotence, increased body heat, increased heart rate, involuntary movements of tongue, face, mouth or jaw (eg, sticking out of the tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes with involuntary movements of the arms and legs, irregular heart rhythm, irregular pulse and blood pressure, mood changes, muscle rigidness, muscle twitching, rash, seizures, slow movements with tremor, sweating, swelling in the throat area, tightness in the lungs, unusual or unexplained vision changes, yellowing of the skin or eyes.

Storage
Store Reglan at 68 – 77 °F (20 – 25 °C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Reglan out of the reach of children.

Overdose
If overdose is suspected seek medical attention immediately. Some of the symptoms of Reglan overdose are- agitation, confusion, and drowsiness, and muscle restlessness, unusual movement of eyes, face, or limbs.

More Information
Reglan may cause drowsiness, dizziness, or blurred vision. These effects may worsen if Reglan is taken with alcohol or certain other medications. Use Reglan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to this drug. If your symptoms do not improve or if they worsen, contact your doctor. Reglan should be used only by the patient for whom it has been prescribed. Do not take less or more or take it more often than prescribed by your doctor.

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